Just the thought of an in-home spider infestation is a nightmare for many, but it's something that can be taken care of and eliminated. While not always physically threatening or dangerous, a spider infestation is often an indicator that other pest populations are present in the home. Spiders like to eat bugs. If your home has populations of roaches, ants, or crickets spiders will be happy to take roost there with an ample supply of food. Consequently, it makes sense to first address the underlying pest problem before tackling the spider issue. Black widows and brown recluse spiders, the most poisonous and dangerous in the US, are the two most significant dangers of spider infestation. A bite from one of these spiders can be deadly.