The Role of Genetics in Endometrial Cancer
Genes can influence the probability of developing endometrial cancer, which affects cancer of the uterus. Some families have a higher chance of getting this cancer because of some alterations in specific genes. A notable condition is Lynch syndrome, which has an endometrial cancer risk in women that ranges between 40-60% in their lifetime. Other genes, such as PTEN and BRCA1/2, can also contribute to increased risk. Knowing these genetic constituents allows healthcare professionals to deliver more targeted treatment and prevention strategies.
